Immunotoxicity testing can be carried out using in vivo and in vitro assays. In contrast to in vivo immunotoxicity testing, possibilities for in vitro testing are limited as the models lack the complexity of the intact immune system. The value of in vitro methods in assisting extrapolation of animal data to man is futher limted bacause they are not yet sufficiently developed and standardized. However, they can be useful as mechanistic studies. An important focus of immunotoxicology is the detection and evaluation of undesired effects of substances by means of tests on rodents.

Immunotoxicity test include:  Cell immunity, Humoral immunity

Down：Bio-degrade test